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Our roots :
 
Interpharma (IPP) is a pharmaceutical and fine chemical producer. IPP was founded in 1932 as a pharmaceutical enterprise and survived the war and 40 years of communism. Today, IPP is associated with Biophysica, Inc. a San Diego, California discovery facility. IPP reduces to practice biomedical, chemical and pharmaceutical research. In 1992, IPP underwent a major transformation. Through its affiliation with Biophysica, involved in the discovery, development and licensing of diagnostics, anti-cancer drugs and other pharmaceuticals worldwide since 1980, IPP employees gained exposure to the ways of modern management and technologies. Thanks to their efforts, the know-how and the technology transfer from the US, new research and development projects made it possible for IPP to expand from a fine chemical and bulk pharmaceutical manufacturer to a developmental company. Research and development activities at IPP are supported by an integrated modern pilot plant and an industrial scale bulk production GMP facility.
Factory site
We are proud that our rebirth was financed without external assistance, solely by reinvesting all of our profits.
Factory site

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Our business:
 
We seek to expand our business and are looking for opportunities to develop and market innovative biomedical pharmaceutical products. IPP offers competitive pricing and fast process development for fine chemicals, pharmaceuticals (APIs) and their intermediates. We offer rapid and professional development of manufacturing technologies and upcoming bulk generics which for legal reasons may not be developed in certain countries prior to the expiration of their patents.
 
Our products include a novel topical anti-androgen for management of androgenetic alopecia, a developmental product for resistant prostate cancer, a boron based neutron capture tumor therapy compound, a number of urologically oriented compounds addressing incontinence, benign prostatic hypertrophy and prevention of prostate cancer, and many others. They are listed and described elsewhere on this website.
 
In the field of Nutraceuticals, IPP has a long tradition of purifying and modifying rutin, a potent antioxidant derived from plants. IPP has excellent analytical and GMP manufacturing experience with complex natural substances such as resveratrol, quercetin, boswellian acids, curcuminoids, baicalin, genistein, diindolylmethane (DIM) and many others. From our sources in Southern France, we have developed total red grape extract enriched with pharmaceutically relevant quantities of Resveratrol Complex. IPP is committed to only such nutraceuticals that are of proven biological value, manufactured under GMP and rigorously analytically controlled.
 
Our people:
 
The management, scientific and production staff are proficient in English and experienced in the development of new technologies for laboratory, pilot-plant and large-scale synthesis. Drawing on the human resources in the Czech Republic known for excellent education in chemistry and pharmaceutical sciences, the personnel of IPP has grown to 108 employees, of whom 18 are working in the state-of-the-art research and development laboratories.

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Our facilities:
 
IPP is a GMP compliant full scale manufacturing facility with state-of-the-art laboratories and an integrated pilot plant. We export DMF-supported APIs and intermediates worldwide and are continuously audited by our customers. We are ISO 9001:2000 certified and FDA approved for export of bulk injectables to the US. English is used as the official language of the Research, Regulatory Affairs and Manufacturing departments.
Laboratory
Our factory has been thoroughly renovated and, to a large degree, replaced. We have 14 production centers and a reactor volume of about 100 m3. There are 75 reactors ranging from 250 to 4000 liters and three 2500 L boilers for the recovery of solvents, a substructure of centrifuges, filter dryers, pumps and multiple drying units. We have a modern power plant authorized to cleanly burn most waste solvents. There is a modern cooling and steam generating system with a combined burner, a dedicated distilled and purified water plant and a recently completed state-of-the-art automatic neutralization and biological treatment of the effluents.
Laboratory
Our GLP and GMP production facility is supported by Quality Assurance unit and state-of-the-art Quality Control analytical laboratories which include a microbiology facility.
Production
We have dedicated facilities for hydroxyethylation, reactions up to 220°C, catalytic hydrogenation up to 20 atm, iodination and preparation of iodomonochloride and sodium iodo-dichloride. We have a distinctive expertise in the technology of handling iodine, iodination, iodine recovery, and x-ray contrast media manufacturing as well as extractions and sophisticated purifications.

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TÜF
 
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